Zoprox 100 tablets

/Zoprox 100 tablets
Zoprox 100 tablets 2018-07-11T06:57:44+00:00

Zoprox 100 dispersible tablet contains cefpodoxime. It is a third generation oral antibiotic. Cefpodoxime is a drug which is active against both gram positive and gram negative bacteria. It is mainly used for otitis media, pharyngitis, sinusitis and gonorrhea.

  • Acute otitis media

  • Acute maxillary sinusitis

  • Community acquired pneumonia

  • Uncomplicated skin and skin structure infections

  • Uncomplicated urinary tract infections

Once daily

Cefpodoxime is active against a broad spectrum of gram positive and gram negative baceteria. It causes inhibition of cell wall synthesis and produces bactericidal activity. Its active metabolite binds to penicillin binding protein 3 which causes inhibition of production of peptidoglycan.


After oral administration the drug is absorbed from gastrointestinal tract. Cefpodoxime is a prodrug, after administration it gets de-esterified to its active metabolite cepodoxime.


About 22 to 33% of the drug is bound to serum, and 21 to 29% of the drug is bound to plasma.


Nearly about 29-33% of the drug is excreted in unchanged form in urine within in 12hrs.

  • Hypersensitivity reaction

  • If patients are penicillin sensitive, caution should be exercised because cross sensitivity among beta lactum antibiotics has been documented and can occur in patients with history of penicillin sensitivity

  • Allergic reaction

  • Other prescription and non prescription drug

  • Patient history of kidney or liver disease and stomach problems

  • In pregnant or breast feeding patient

  • Patient with surgery like dental surgery

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