Zazid 250 injection

/Zazid 250 injection
Zazid 250 injection 2018-07-13T04:14:21+00:00

Zazid 250 injection contains ceftazidime. Ceftazidime is a third generation cefphalosporon antibiotic which is useful for the treatment of infections caused by the bacteria. It is active against pseudomonas and has improved stability against beta-lactamase enzyme producing bacteria.

  • Wide variety of bacterial infections

  • It stops the growth of bacteria

  • Lower respiratory tract infections caused by pseudomonas aeruginosa

  • Skin and skin structure infections

  • Bacterial septicemia

  • Urinary tract infections

  • Gynecological infections

  • Bone and joint infections

  • Central nervous infections including meningitis caused by H.influenza

30 to 50 mg/kg IV every 12 hours for four weeks

It produces its action by binding to penicillin binding protein and causes inhibition of the cell wall synthesis.


After administration the normal serum concentration in healthy individual is 45-90mcg/ml. The time required to pharmacological action is about 20-30mins.


Less than 10% of the drug is bound to plasma protein.


The drug is excreted through kidney with higher concentration in urine.

  • Hypersensitive to ceftazidime or any cephalosporin

  • Prolong use can cause reduced renal sufficiency

  • Increased levels of cetazidime can cause seizers, coma or neuromuscular excitability

  • Administration of cetazidime with other antibiotics can cause overgrowth of non susceptible organism

  • Can cause fall in prothrombin activity

  • Use the drug if clearly needed

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