Ventace syrup contains acebrophylline. It is a xanthine derivative. It is a bronchodilator which is used for the treatment of bronchial asthma. It produces its action by causing alteration in mucus secretion by lowering the viscosity of the mucus. It is also helpful in mucociliary clearance.
Mucoregulator
Anti-inflammatory agent
In obstructive airway disease
Acute or chronic bronchitis
Asthma like bronchitis
Improves indexes of ventilatory function
Half a teaspoon, three times a day for 2 to 5 yrs of age
Acebrophylline produces its action by inhibiting phospholipase A and phosphatidycholine which causes lesser production of powerful pro-inflammatory substances. It reduces inflammation by inhibiting the synthesis and release of inflammatory mediators and helps in airway obstruction.
Absorption
After oral administration the drug is well absorbed
Distribution
After oral administration the drug is released in the stomach in two forms i.e ambroxol and theophylline which is absorbed in intestine. The Cmax is attained within 2hrs. The plasma life is 4 to 9hrs. The metabolism of the drug is through liver.
Excretion
The drug is excreted through kidney
Hypersensitivity to any of the ingredient
Patient with acute myocardial infarction
Hypotension
Hemodynamic instability
Arrhythmias
Renal and hepatic disease
Not to be used in hypotensive patients
Acute myocardial infarction
Cardiac insufficiency
Convulsions
GI disturbances
Hepatic and renal disorder
