Rexol 125 suspension contains paracetamol. It is also known as acetaminophen and is widely used as over the counter analgesic and anti-pyretic. It is a mild analgesic which causes relief in mild headaches and other aches and pains. In combination with other drugs like opioid analgesic, paracetamol is used in the management of post surgical pain and severe pain.
Acute pain
Analgesic
Anti-pyretic
Migraine headaches
Dysmenorrhea
Joint pain
Four times a day.
It inhibits the synthesis of prostaglandin synthesis by competing with arachidonic acid for the active site of COX.
Absorption
It has rapid and complete absorption
Distribution
The protein binding of the drug is about 25%, it undergoes glucuronidation in liver.
Excretion
About 80% of acetaminophen is excreted in the urine after conjugation and about 3% of the drug is excreted unchanged.
Liver Failure
Liver Problems
Serious Kidney Problems
Shock
Overdose of the Drug Acetaminophen
Poor Nutrition
Any allergies
Liver disease
Alcohol abuse
Chewable tablet may contain sugar or aspartame should not be used in diabetic patients
